Resistance Changes of Escherichia Coli to Cephalosporin in Erbil

Sirwan, Yad (2022) Resistance Changes of Escherichia Coli to Cephalosporin in Erbil. Eurasian Journal of Science & Engineering, 7 (2). pp. 186-193. ISSN 2414-5602

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Abstract

Antibiotic resistance is a topic that is constantly being researched, and numerous studies are published each year with new data that can change or redefine our perspective on the problem. The emergence and spread of drug-resistant pathogens with new resistance mechanisms, leading to antimicrobial resistance, continue to jeopardize our ability to treat common infections. This necessitated the need for understanding the mechanism of action in each country due to the environmental changes. The study aimed at documenting the resistance of E. coli to Cephalosporin in Erbil, Kurdistan Region of Iraq. The study covers the periods from August to December 2018. Two hundred and two (202) samples were collected from infected patients in Erbil from different specimens. Four different groups of cephalosporin were tested against the resistance of E. coli. Ineffectiveness of the antibiotics used against E. coli was reported. E. coli is becoming stronger every month, according to our findings. The rising increase in the resistance of E. coli is a result of resistance to fluoroquinolones in E. coli, which causes other resistance mechanisms because it is often linked to other commonly used medicines. There is a need for proper investigation of E. coli resistance to the currently used antibiotic in each country because the continued resistance might require to change guidance of many severe infections. Continued research on medicinal plants is also needed to develop a compound against resistant microorganisms.

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