Biological Evaluation of Garcinia kola Heckel

Abdulrahman, M.D. and Ali Hama, Harmand and W. Hamad, Saber and S. Al-Rawi, Sawsan and Kayfi, Soran (2022) Biological Evaluation of Garcinia kola Heckel. Advances in Pharmacological and Pharmaceutical Sciences.

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Abstract

Garcinia kola belongs to the Garcinia genus of the Clusiaceae family and Malpighiales order. It contains more than 180 members all over the globe. It is found all over Asia and in tropical African countries. In Africa, traditionally, G kola is used to manage and treat cancer, diabetes, malaria, analgesics, hypertension, and other numerous ailments. �is review aimed to comprehensively update relevant information regarding the pharmacological potential of Garcinia kola. Electronic databases such as ScienceDirect, PubMed, Wiley, Google Scholar, Hindawi, and Springer extracted valuable information from original scienti�c research papers. Inclusion Criteria. Antioxidant, antimicrobial, antidiabetic, antibacterial, medications, antiviral, traditional medicine, ethnopharmacology, toxicity, cytotoxic action, chemical composition, mineral elements, GCMS analysis, and any other related phrases were used as �lters to �nd studies. Exclusion Criteria. Data from questionable online sources, as well as thesis reports and review publications, were excluded from this investigation. �e investigation revealed that seeds of G. kola are very e�cient as antioxidant, antimicrobial, antidiabetic, antihypertension, antianalgesic, and anti-in�ammatory. �e study also found that too much consumption of the seeds caused low fertility and toxicity. However, the safety and e�cacy of G. kola have not been wholly assessed in humans, and further well-designed clinical trials are needed to corroborate preclinical �ndings. �e mechanism of action of the seed extract should be examined. �e standard dose and safety of the seed should be established

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