Phytochemical Screening of Different Parts of Prangos Platychlaena Boiss by Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Ozdemir, Mehmet and Ahamad, Javed and H.S. Hussain, Faiq (2021) Phytochemical Screening of Different Parts of Prangos Platychlaena Boiss by Liquid-Chromatography Tandem Mass Spectrometry (LC-MS/MS). Eurasian Journal of Science & Engineering, 7 (2). pp. 30-38. ISSN 2414-5602

[img] Text (Research Article)
eajse.v7i2p30.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (1MB)
Official URL:


Liquid-chromatography tandem mass spectrometry (LC-MS/MS) is a hyphenated analytical technique that combines the separating power of liquid chromatography with mass analysis capabilities. The aim of present study to identify and characterize different chemical compounds present in different (roots, leaves, stems and flowers fractions) parts of Prangos platychlaena Boiss. (family: Apiaceae) by LC�MS/MS method. The LC-MS/MS analysis for identification and characterization of phytocompounds in different extracts were performed, and that leads identification of five new compounds first time in P. platychlaena plant and they were psoralen, bergapten, 5,8-dimethoxy psoralen, isoimperatorin and pthalic acid mono-2-ethylhexyl ester. The identification and characterization of phytocompounds were performed on the basis on mass spectroscopy data and literature reports. The LC-MS/MS method was found simple and fast for identification and characterization of phytocompounds in different extracts of P. platychlaena.

Item Type: Article
Uncontrolled Keywords: Ahamad, J., Mir, S.R., Kaskoos. R.A., & Ahmad, J. (2020). Proteomics for food authentication. (Edited by Leo M.L. Nollet, Semih Ötleş), Chapter 11: Proteomics in Authentication of Wine. CRS Press, Taylor & Francis Group. Ahamad, J., Naquvi, K.J., Ali, M., & Mir, S.R. (2013). New glycoside esters from the aerial parts of Artemisia absinthium Linn. The Natural Products Journal, 3(4): 260-267. Ahamad, J., Naquvi, K.J., Ali, M., & Mir, S.R. (2014). Isoflavone glycosides from aerial parts of Artemisia absinthium Linn. Chemistry of Natural compounds, 49(6), 696-700. Ahmed, J., Guvenc, A., Kucukboyaci, N., Baldemir, A., & Coskun, M. (2011). Total phenolic contents and antioxidant activities of Prangos Lindl. (Umbelliferae) species growing in Konya province (Turkey). Turkish J. Biology, 35, 353-360. Cesur, C., Coşge Şenkal, B., Yaman, C., Uskutoğlu, T., & Koç, M. (2017). Antioxidant activity of fruit extracts of Prangos ferulacea (L.) Lindl. from Turkey. J. the Institute of Science and Technology, 7, 249-256. Farooq, S., Shakeel U.R., Dangroo, N. A., Priya, D., Banday, J.A., & Sangwan, P.L. (2014). Isolation, cytotoxicity evaluation and HPLC-quantification of the chemical constituents from Prangos pabularia. PLoS One, 9, 1-9. Ghazanfar, S.A., & Edmondson, J.R. (2013). Flora of Iraq. National Herbarium of Iraq of the Ministry of Agriculture, Baghdad, 5, 109-220. Hamad, R., Balzter, H., & Kolo, K. (2017). Multi-criteria assessment of land covers dynamic changes in Halgurd Sakran national park (HSNP), Kurdistan region of Iraq, using remote sensing and GIS. Land, 6, 1-17. Kafash-Farkhad, N., Asadi-Samani, M., & Rafieian-Kopaei, M. (2013). A review on phytochemistry and pharmacological effects of Prangos ferulacea (L.) Lindl. Life Science Journal, 10, 360-367. Massumia, M.A., Fazelib, M.R., Alavic, S.H.R., & Ajanid, Y. (2007). Chemical constituents and antibacterial activity of essential oil of Prangos ferulacea (L.) Lindl. Fruits. Iranian Journal of Pharmaceutical Sciences, 3, 171-176. Mir, S.R., Tahir, T.F., Ahamad, J., Kaskoos, R.A., Alkefai, N.H.A., & Samad, A. (2020). Bioactive Phytochemicals: Drug Discovery to Product Development. Chapter 5: Spectroscopic Techniques for Structural Characterization of Bioactive Phytochemicals. Bentham Books. Mottaghipisheh, J., Kiss, T., Toth, B., & Csupor, D. (2020). The Prangos genus: a comprehensive review on traditional use, phytochemistry, and pharmacological activities. Phytochem. Rev., 19, 1449-1470. Naquvi, K.J., Ahamad, J., Kaskoos. R.A., Alkefai, N.H.A., Salma, A., & Mir, S.R. (2020). Bioactive Phytochemicals: Drug Discovery to Product Development. Chapter 4. Isolation and Purification of Bioactive Phytochemicals. Bentham Books. Nosrati, M., Behbahani, M., Mohabatkar, H., & Shakeran, Z. (2018). Antibacterial and antibiofilm activities of Prangos acaulis Bornm. extract against Streptococcus mutans: an in silico and in vitro study. J. Herbmed Pharmacology, 7, 176-184. Rahman, J.K., & Jaff, D.M. (2020). Variation in phytochemical, physiochemical contents and toxicity of Prangos platychlaena Boiss in Halgurd mountain of Iraqi Kurdistan. Iraqi Journal of Agricultural Sciences, 51(3), 443-453. Rahman, J.K., Jaff, D.M., & Dastan, D. (2020a). Prangos platychlaena Boiss essential oils: A novel study on its toxicity, antibacterial activity and chemical compositions effect on burn rats. Iraqi J. Agricultural Sciences. 51(1), 519-529. Rahman, J.K., Jaff, D.M.A., Basar, N., Kuthi, N.A., & Yaqunu, R. (2020b). Phytochemical screening, isolation of coumarins and bioactivity of Prangos platychlaena Boiss. Plant in Iraq. Applied Ecology and Environmental Research, 18(2), 2425-2443 Sharma, N., Ashok, P.K., & Negi, A. (2013). A review on ethnobotany, phytochemical and pharmacological dynamics of Prangos pabularia Lindl. J. Natural Remedies, 13, 68-75. Shokoohinia, Y., Sajjadi, S.E., Gholamzadeh, S., Fattahi, A., & Behbahani, M. (2014). Antiviral and cytotoxic evaluation of coumarins from Prangos ferulacea. Pharmaceutical Biology, 52, 1543-1549. Ulubelen, A., Topcu, G., Tan, N., Olcal, S., Johansson, C., Llger, M., & Tamer, B.H. (1995). Biological activities of a turkish medicinal plant, Prangos Platychlaena. J. Ethnopharmacol., 45, 193-197. Uzel, A., Dirmenci, T., Celik, A., & Arabaci, T. (2006). Composition and antimicrobial activity of Prangos platychlaena and P. uechtritzii. Chemistry of Natural Compounds, 42, 169-171. Yeo, Y. L., Chia, Y.Y., Lee, C.H., Sow, H.S., & Yap, W.S. (2014). Effectiveness of maceration periods with different extraction solvents on in-vitro antimicrobial activity from fruit of Momordica charantia L. J. Applied Pharmaceutical Science, 4, 16-23. Yousefi, K., Hamedeyazdan, S., Hodaei, D., Lotfipour, F., Baradaran, B., Orangi, M., & Fathiazad, F. (2017). An in vitro ethnopharmacological study on Prangos ferulacea: a wound healing agent. Bioimpacts, 7, 75-82.
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Q Science > QR Microbiology
R Medicine > RK Dentistry
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Eurasian Journal of Science and Engineering > VOL 7, NO 2 (2021)
Depositing User: ePrints deposit
Date Deposited: 08 Mar 2022 10:26
Last Modified: 08 Mar 2022 10:26

Actions (login required)

View Item View Item